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Introduction: Serum Anti-Mullerian Hormone (AMH) and antral follicle count (AFC) are currently the most utilised ovarian reserve markers. Ovarian aging relates to the decline in the quality and quantity of the ovarian follicle pool and manifests as decreasing spontaneous fecundity and low fertility treatment success with advancing age. There is considerable variation in ovarian aging between individuals and wide distribution of AMH and AFC results reported with age. This is largely due to the varying initial oocyte numbers at birth and varying pace of follicular recruitment/apoptosis between individuals. Studies indicate that young women with low ovarian reserve markers may experience a decline in fertility causing a shift towards premature ovarian failure or early menopause. Aims and objectives: This study aims to investigate the proportion of young infertile women with a low ovarian reserve and to make age-specific percentile charts of AMH and AFC amongst Indian infertile women. The results may provide reliable information with respect to a woman's ovarian reserve within a given age category and guides to counsel the prognosis related to fertility. Materials and methods: This is a retrospective cross-sectional study from January 2023 to December 2023. Study included 448 subjects of age group 21-44 years. Ovarian reserve markers provided a critical reference for early ovarian insufficiency, which would greatly facilitate to identify patients of high risks and timely guide family planning and fertility intervention. The age-specific cut off values were not available. Analysis of serum AMH on day 2 or day 3 of menstrual cycle was determined in venous blood at a single laboratory with an ultrasensitive enzyme-linked immunosorbent assay (ELISA) in a concentration of ng/ml. AFC was measured in both ovaries on day 2 or day 3 of the menstrual cycle. Measurement of AFC included counting identifiable follicles with a mean diameter ranging from 2 to 10 mm in both the ovaries. Result: The median age of women in the sample (n = 448) was 32 years of age ranging between 21?44 years. Serum AMH and AFC below the 10th percentile for the age indicates poor/low ovarian reserve. In this study, the 10th centile of AMH was 1.34 ng/ml in women <25 years of age and 0.04 ng/ml in women aged >40 years of age. The 10th centile of AFC was 9 and 3, respectively, for these two age groups. This study revealed that 14.5% of women <35 years of age and 50.5% of women more than 35 years of age presented with low AMH values (<1.2 ng/ml). Conclusion: Ovarian reserve mainly encompasses the quantity and quality of oocytes. It determines woman?s reproductive potential, reproductive lifespan and age of onset of menopause. The age-specific cut off values of ovarian reserve markers provided a critical reference for early ovarian insufficiency, which would greatly facilitate to identify patients of high risks and timely guide family planning and fertility intervention.