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Purpose: To assess the role of total serum estradiol on the day of injection HCG (trigger) and it?s correlation to mature follicle (M2) obtained Methods: A retrospective observational study, inclusion being all patients who underwent IVF cycles in our institute over 6 months. Results: 218 IVF cycles from our database studied, having maximal causes of infertility being tubal factor (34.2%) while 15 % having more than 1 factor. Mean age being 34 +/- 2 years. A positive correlation between E2 obtained on day of HCG trigger and M2 oocytes obtained (of 0.48) using Paerson?s coefficient of variance test. Conclusion: Controversy exists about the benefit of measuring E2, our study highlights that it can be correlated to M2 obtained and hence useful for patient counseling.