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INTRODUCTION-The anomalous foetus and the decisions made about its management could affect the normal co-twin, adding to the already increased perinatal morbidity and mortality in twin gestations. OBJECTIVE - To study the types of discordant anomalies in twin pregnancies and their perinatal outcome METHODS ? It is a retrospective analysis of all twin pregnancies with diagnosis of discordant anomaly diagnosed on ultrasound and confirmed after delivery or termination over 10 years from 2014 to 2023 at JIPMER, Puducherry. The findings secondary to TTTS and TRAP sequence were excluded from the study. The demographic details, antenatal course of pregnancy, any intervention done and perinatal outcome in the form of NICU admission, neonatal surgery and mortality of either twins were studied. RESULTS ? The prevalence of discordant anomalies in twin pregnancies at our institute was 1.75% (n=60/3411). Out of these, the majority (70%) were dichorionic twins and 30% (n=18) were monochorionic twins. The major system involved were either CNS or cardiovascular system. Majority were detected at the time of target scan at 18-20 weeks and 21/58 (36.2%) were detected after 24 weeks. Three DADC twins underwent selective fetal reduction : two had anencephaly and one had cloacal dystrophy. The neonatal survival rate of the anomalous co-twins at one month after birth was only 33% (n=18/54), while it was 88.3% for normal co-twins. CONCLUSION ? While the neonatal survival of anomalous twin is low, the survival rate of normal co-twin is high even after expectant management.