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Title: PREDICTIVE VALUES OF 1ST TRIMESTER HBA1C FOR GDM
e-poster Number: EP 370
Category: Maternal and Fetal Health
Author Name: Dr. Dipika Digdarshini Biswal
Institute: SCB MEDICAL COLLEGE
Co-Author Name:
Abstract :
? INTRODUCTION : Gestational diabetes mellitus is defined as glucose intolerance of any degree with onset or first recognition during pregnancy.About 1%-14% of all pregnancies are complicated by DM and out of them 90% were GDM worldwide.MoHFW Government of India recommends universal screening policy.Diabetes In Pregnancy Study group of India (DIPSI) is a single step test and best screening method for GDM. 75 gm glucose is dissolved in approximately 300 ml water irrespective of the last meal and completed within 10 minutes. This test is done as per DIPSI guideline. HbA1c is most useful for pre conceptional counselling and to predict fetal outcome .The potency of HbA1C level in the first trimester as a novel predictor of gestational diabetes mellitus in pregnant patients.Thus it is necessary to integrate the use of HbA1C level screening as a part of antenatal care in the first trimester of pregnancy. Women with higher first trimester HbA1C have a high risk for GDM. This helps in preventing long term sequelae of GDM and adverse pregnancy as well as perinatal outcome. MATERIAL AND METHOD Study Population-The patients attending antenatal OPD or maternity ward in the first trimester at SCB medical college and hospital. Place of Study-Dept. of O & G, SCB Medical College & Hospital. Duration of Study - 1.5 years (from JUNE 2023 to OCTBER2024). Study Design-Prospective Cohort Study RESULT The cut off point first trimester HbA1C for predicting GDM is 5.75.It?s sensitivity is 67.7% and specificity is 97.7%.The mother whose first trimester HbA1C value is >5.75 have (82%) chance of developing GDM whereas only 40% chance of developing GDM in mother who have HbA1C <5.75.In case of GDM mother the FBS and PPBS value in second and third trimester is higher than NON GDM mother.The chance of developing GDM in mothers having HbA1C value in betwwn (4.5-5.0),(5.1-5.5),(5.6-6.0) and (6.1-6.4) are 8%,22%,57%,90% respectively. CONCLUSION In conclusion, a short-term intensive care gives a long term pay off in the primary prevention of obesity, impaired glucose tolerance and diabetes in the offspring as preventive medicine starts before birth.