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This case report concerns a primigravida woman (period of gestation-37 weeks) diagnosed with intrahepatic cholestasis of pregnancy (IHCP). She had been married since 2 years and this is her first pregnancy. The patient is an Rh-negative mother. She did not receive anti-D at 28 weeks of gestation. The patient was admitted to antenatal ward of Hakeem Abdul Hakeem Centenary (HAHC) Hospital, New Delhi, with chief complaints of itching all over the body since 15?20 days with severe itching over the umbilical area and presence of rashes on legs and breasts since last 10 days. During the physical examination the rashes were seen on legs and breast. Per abdomen examination revealed cephalic presentation of the fetus with FHR as 140 bpm. Routine blood investigations revealed that the patient was also a case of moderate anemia and the blood group of the patient was AB-negative. After all the required investigations, she was diagnosed with IHCP with moderate anemia with Rh-negative pregnancy. IHCP is a pregnancy-specific liver disorder characterized by pruritus, most often, in the late-second or early third trimester of pregnancy and raised serum bile acids. The maternal outcome after treatment is good but fetal outcomes become adverse in most of the conditions.