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Title: A CASE OF INFANTILE PRECOCIOUS PUBERTY
e-poster Number: EP 050
Category: Sexual and Reproductive Health and Rights and Contraception
Author Name: Dr. Shashi Prabha Singh
Institute: Dr B R Ambedkar Medical College
Co-Author Name:
Abstract :
Precocious puberty, marked by the early onset of secondary sexual characteristics, poses unique challenges in infants due to the potential psychosocial impacts and risk of compromised adult height. This report describes a rare case of central precocious puberty (CPP) in a 1-year 6-month-old female baby presenting with cyclical vaginal spotting for 10 months. The baby?s mother noted regular, painless 2-day bleeding episodes occurring every 30 days, with no associated symptoms or history of trauma or abuse. At presentation, the baby weighed 16.5 kg and was 93 cm tall. Physical examination revealed breast development (Tanner stage 2) and sparse axillary and pubic hair (Tanner stage 2), with otherwise normal external genitalia and systemic findings. Ultrasonography revealed a mildly enlarged uterus with increased endometrial thickness, along with a dominant follicle in the right ovary. Elevated basal gonadotropin levels and normal MRI findings supported the diagnosis of CPP. The baby received a single dose of Medroxyprogesterone (50 mg) intramuscularly, followed by three-monthly Leuprolide injections for GnRH suppression. Cyclical bleeding resolved post-treatment; however, secondary sexual characteristics persisted. Continued GnRH therapy is planned until age 10?11 to delay pubertal progression and optimize growth outcomes. This case emphasizes the importance of early recognition, targeted diagnostic workup, and tailored management of CPP in very young children to mitigate potential long-term effects on physical and psychosocial development.