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Introduction - Gestational trophoblastic disease is term used to encompass a group of tumors typified by abnormal trophoblast proliferation. The malignant forms of GTD are termed gestational trophoblastic neoplasia (GTN). These include invasive mole, choriocarcinoma, placental site trophoblastic tumor, and epithelioid trophoblastic tumor. These malignancies develop weeks or years following any type of pregnancy, but more frequently follow hydatidiform mole. Aims and objective - This poster presents a review of the clinical features, diagnostic approaches and management of Choriocarcinoma. Materials and methods - A 25 year old female with previous 1 LSCS ,P1L1A1 post suction evacuation day 23 came with complaints of per vaginal bleeding since 1 day. On admission patient was vitally stable with moderate anemia(Hb -8.3) . In the past , patient had conceived spontaneously after previous pregnancy and diagnosed as partial mole on dating scan .Patient underwent suction evacuation for same and received one packed cell transfusion. On day 10 post evacuation her beta hCG was 10,000. On day 23 beta HCG was 71399. Chest X ray done which showed no metastasis .Endometrial sample sent for histopathological examination. Results -The patient was started on antibiotics and Inj Methotrexate (1gm/kg body weight) 3 doses on alternate days with Inj Folinic acid . One pint packed cells transfused . Histopathological report revealed persistent trophoblastic disease- Choriocarcinoma. Patient advised chemotherapy and still under follow up. Conclusion - During beta hCG levels surveillance , increasing or plateaued levels mandate evaluation for GTN.If the woman has not become pregnant, these levels signify trophoblast proliferation that is most likely malignant . Therefore a careful evaluation of Beta hCG levels , tissue biopsy, tests for liver and renal function , transvaginal sonography , chest radiography and brain CT OR MR imaging helps identify local disease , metastasis and staging of GTN.