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INTRODUCTION Uterine artery embolization has been tried as treatment modality in selected cases of invasive molar pregnancy along with suction evacuation and chemotherapy in women desirous of fertility. Secondary amenorrhea is a long-term complication and we have evaluated on such case. CLINICAL CASE A 20-year-old A1 was diagnosed with invasive mole 3 years ago with ?-hcg level of 7,50,000 and TSH of 0.01. A multidisciplinary approach consisting of uterine artery embolization followed by therapy with Methotrexate/Leucoverin, Suction evacuation and post operative chemotherapy was used to treat her. She presented to our hospital with a history of years of secondary amenorrhea. Clinical examination showed normal size uterus. Her routine blood counts, renal, liver, thyroid function tests, Serum prolactin levels and test for ovarian reserve were within normal limits. MRI Pelvis showed indistinct junctional zone in upper part of uterus with increased myometrial signal intensity in fundus and upper half of uterus suggestive of possible post uterine artery embolization change. Endometrial thickness could not be assessed. Given this clinical picture and 2 years of multiple treatment attempts, Asherman syndrome was suspected and Diagnostic hysteron-laparoscopy proceeded. Hysteroscopy showed presence of synechiae near the cervical internal os and dense adhesions. Adhesiolysis proceeded and ostia were visualized. Endometrium appeared atrophic. Diagnostic laparoscopy was proceeded which showed an irregular, scarred, variegate appearing uterus. Bilateral tubes appeared normal and ovaries appeared polycystic. Chromopertubation proceeded and bilateral spill was present. Intraoperatively we inserted Copper T and started a trial Oral Conjugated Estrogen 0.625mg and Oral Dyhydrogesterone 10mg for this patient to aid in regeneration of endometrium. Three months following therapy the patient had one episode of spotting per vaginum and towards the end of 6 months the patient had 2 cycles of menstruation with 2 days of bleeding. Though serial ultrasound imaging endometrial regeneration was identified. CONCLUSION Uterine artery embolization used as a uterus conserving therapeutic measure can result in secondary amenorrhea and scarred uterus which requires prolonged hormonal therapy to attain partial endometrial regeneration.